Biosensors & Bioelectronics

Peter A Lieberzeit

Publications

• Research Article
  Blood Coagulation Thromboplastine Time Measurements on a Nanoparticle Coated Quartz Crystal Microbalance Biosensor in Excellent Agreement with Standard Clinical Methods
  Author(s): Munawar Hussain, Stefan Sinn, Martin Zeilinger, Hinnak Northoff, Peter A Lieberzeit and Frank K GehringMunawar Hussain, Stefan Sinn, Martin Zeilinger, Hinnak Northoff, Peter A Lieberzeit and Frank K Gehring
  
  Measurements of parameters of hemostasis like thromboplastine time (PT) have primary significance in many clinical settings including extensive surgery, dialysis or innate disorders of hemostasis. Recently, several reports have documented the principle suitability of Quartz Crystal Microbalances (QCM) for measuring parameters of hemostasis like PT or platelet aggregation. But for the establishment of an exact QCM based method as alternative to standard coagulometer measuring QCM coatings with significantly enhanced robustness and reusability have to be worked out. For this purpose we utilized a new semi-automated equipment qCell T for measuring and compared different coatings consisting of polymer films and absorbed nanoparticles (NPs). We demonstrated that affinity based poly ethylene NPs absorbed to polymer films on the QCM constitute a powerful tool with no need for pretreatment fo.. Read More»
  DOI: 10.4172/2155-6210.1000139

  Abstract PDF