Centre Hospitalier de l’Université de Montréal,
Montréal, Québec
Canada
Case Report
Fluctuating Hearing Loss Responding to Corticosteroids: A Case of
Cogans Syndrome Concomitant with Crohns Disease
Author(s): Philippe Desmarais and Mikhael LaskinePhilippe Desmarais and Mikhael Laskine
Hearing loss has a broad differential diagnosis. Hearing impairment responding to corticosteroids is suggestive of an underlying autoimmune cause. We report a rare case of Cogan’s syndrome in a 28-year-old woman with no previous personal medical history. She had experienced two years of fluctuating hearing loss and bilateral keratitis that would respond to high-dose prednisone prescribed by her otorhinolaryngologist. We performed a complete work-up and ruled out most common causes of autoimmune inner ear diseases. Patient was diagnosed with Cogan’s syndrome based on clinical findings and prescribed corticosteroid-sparing immunosuppressive medication. During follow-up, she developed worsening fatigue, new onset anemia, and melena. Endoscopic and pathologic findings were diagnostic of Crohn’s disease. This case emphasizes the high prevalence of concomitant autoimmune d.. Read More»
DOI:
10.4172/2165-7920.1000810
Journal of Clinical Case Reports received 1345 citations as per Google Scholar report