Colombo South Teaching Hospital,
Kalubowila
Sri Lanka
Case Report
A Rare Case of Focal Segmental Glomerulosclerosis in a Patient with
Grade a Benign Thymoma: A Case Report and Review of the Literature
Author(s): Prashan Buddhika Illeperuma and Ananda JayanagaPrashan Buddhika Illeperuma and Ananda Jayanaga
Thymoma is a rare mediastinal tumour that is often (40%) accompanied by different paraneoplastic syndromes and glomerulonephritis is one of the recognized entities. Minimal change disease is the most common paraneoplastic glomerulonephritis associated with thymoma, followed by membranous nephropathy, focal segmental glomerulosclerosis, rapidly proliferative glomerulonephritis and lupus nephritis. Literature review illustrates that most of the thymoma associated nephropathy cases were reported in association with more malignant thymic tumors like WHO grade B and C tumours. Herein we report a rare case of focal segmental glomerulosclerosis in a patient with grade A benign thymoma, a combination which has never been reported previously. She had poor response to corticosteroids and died due to neutropenic sepsis following azathioprine the.. Read More»
DOI:
10.4172/2165-7920.1000794
Journal of Clinical Case Reports received 1345 citations as per Google Scholar report