Journal of Computer Science & Systems Biology

Prashant K Mishra

Publications

• Research Article
  Functional Analysis of Hypothetical Proteins of Chlamydia Trachomatis: A Bioinformatics Based Approach for Prioritizing the Targets
  Author(s): Prashant K Mishra, Subash C Sonkar, Sree Rohit Raj, Uma Chaudhry and Daman SalujaPrashant K Mishra, Subash C Sonkar, Sree Rohit Raj, Uma Chaudhry and Daman Saluja
  
  The various genome sequencing projects have led to the accumulation of entire set of gene sequences of many organisms. Among the sequenced genomes are numerous genes which code for proteins of unknown function. These genes are termed as hypothetical genes and their corresponding gene products are known as Hypothetical Proteins (HPs). Analyzing and annotating the functions of these HPs is important in pathogenic organisms such as Chlamydia trachomatis that causes various sequelae of diseases by infecting different sites in humans. Functional annotations of these HPs provides insights into their exact molecular function and may help in identification of novel drug or vaccine candidates for the control of infections caused by C. trachomatis. In the present study, entire set of 336 HPs of C. trachomatis were retrieved from NCBI and analyzed for their function .. Read More»
  DOI: 10.4172/jcsb.1000132

  Abstract PDF