India
Research Article
A Correlative Study on Hepatitis C Virus Load Determined by Real Time Polymerase Chain Reaction with Serum Biomarkers in Patients with Renal Disease
Author(s): Bagyalakshmi R, Malathi J, Prathiba K, Samson Y, Ravichandran R and Madhavan HNBagyalakshmi R, Malathi J, Prathiba K, Samson Y, Ravichandran R and Madhavan HN
Purpose: To determine the Hepatitis C virus (HCV) load in peripheral blood specimens of patients with renal abnormality reporting to the nephrology unit and to correlate the viral load with different biomarkers in serum.
Materials and Methods: Fifty peripheral blood specimens were obtained from patients reporting to the nephrology unit and these patients were categorized into three groups as Group I: Renal Transplant patients, Group II: Dialysis patients, Group III: Other patients. with elevated liver enzymes and renal pathology. Peripheral blood specimens collected from kidney transplant recipients (n = 11), dialysis (n=17) and others (n =22) were subjected to detection of antibodies to HCV, determination of viral load by Real Time PCR and biochemical profiling consisting of estimation of bilirubin, total protein, alanine aminotransferase, an.. Read More»
DOI:
10.4172/2155-9929.1000123
Molecular Biomarkers & Diagnosis received 2054 citations as per Google Scholar report