Journal of Bioanalysis & Biomedicine

Prathyusha M

Publications

• Research Article
  Hepatoprotective Effect of Inularacemosa on Hepatic Ischemia/reperfusion Induced Injury in Rats
  Author(s): Prathyusha M, Rajesh Indala, Anup Jagaralmudi and Ramesh kumar KPrathyusha M, Rajesh Indala, Anup Jagaralmudi and Ramesh kumar K
  
  Introduction: Hepatic Ischemia-Reperfusion (I/R) injury contributes to organ injury and dysfunction after hepatic surgery and transplantation. I/R induce Kupffer cell activation, leading to the release of pro-inflammatory cytokines that promote injury, increase adhesion molecule expression, and facilitate polymorphonuclear neutrophil injury. Inularacemosa contains high concentrations of the flavonol glycosides, which has been shown effect on cardiac function and oxidative stress against isoproterenol – induced myocardial infarction. Historically, the roots were reputed to have Anti-inflammatory and Analgesic effects. The hepatoprotective activity of the drug against hepatic Ischemia/Reperfusion injury has not been reported yet. Objective: To study the hepatoprotective effect of hydroalcholic extract of Inularacemosa a.. Read More»
  DOI: 10.4172/1948-593X.1000076

  Abstract PDF