College of Basic Sciences and Humanities,
Ludhiana-141 004, Punjab
India
Research Article
Effect of Imidacloprid on Reproduction of Female Albino Rats in Three Generation Study
Author(s): Prerna Vohra and Kuldeep Singh KheraPrerna Vohra and Kuldeep Singh Khera
In the present study, the effect of oral administration of imidacloprid over three generations on biochemical, histological and physiological alterations in female rats was assessed. Female rats were divided into three groups. Group 1 was control and was given corn oil, group 2 was administered imidacloprid at the rate of 10 mg/kg bw/day, group 3 was administered imidacloprid at the rate of 20 mg/kg bw/day. F0 and F1 generation female albino rats were dissected for this study. Weight of ovary decreased significantly at higher dose of treated female rats of F0 and F1 generation. Histopathology of ovary of group 2 and group 3 revealed different stages of follicles. The level of acid phosphatase (ACP) and alkaline phosphatase (ALP) increased significantly at higher dose in the ovary of females of both the generations. In either generation, non-significant changes were observed in fertili.. Read More»
DOI:
10.4172/2157-7579.1000340
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