MD Anderson Cancer Center, Cooper Mount Laurel,
NJ 08054
Tanzania
Research Article
Assessment of Brain Tumor Displacements after Skull-based Registration: A CT/MRI Fusion Study
Author(s): Qianyi Xu, George Hanna, Yongjun Zhai, Sucha Asbell, Jiajin Fan, Tamara LaCouture, Yan Chen, Leonard Kim and Gregory KubicekQianyi Xu, George Hanna, Yongjun Zhai, Sucha Asbell, Jiajin Fan, Tamara LaCouture, Yan Chen, Leonard Kim and Gregory Kubicek
Purpose: To assess brain tumor displacements between skull based and soft-tissue based matching during CTMRI fusion for a total of 35 brain lesions.
Methods: Twenty-five patients who underwent CT and MRI scans in the same day were retrospectively recruited into the study. Semi-automatic skull based fusion was first performed and reviewed on a Treatment Planning System (TPS). A secondary fine-tuning of the fusion was then performed, if mismatch was observed in the tumor or neighboring soft-tissue, using nearby visible soft-tissue, such as gyri, sulci, and fissures. Two physicists fine-tuned the secondary fusion until the best match could be agreed upon. The resulting rotations and translations between the two fusions were recorded, which indicated local displacements between skull based and soft-tissue based matching. We further created a PTV by expanding a 2 mm margin around t.. Read More»
DOI:
10.4172/2155-9619.1000265
Nuclear Medicine & Radiation Therapy received 706 citations as per Google Scholar report