Human Genetics & Embryology

Qiuying Sha

Publications

• Review Article
  Literature Reviews on Methods for Rare Variant Association Studies
  Author(s): Shurong Fang, Shuanglin Zhang and Qiuying ShaShurong Fang, Shuanglin Zhang and Qiuying Sha
  
  The widespread availability of genome sequencing data has yielded different rare variant association methods in population-based or family-based designs. However, it is challenging to know which method is appropriate in practice. Our purpose of this paper is to provide a general review of the literature for rare variant association studies and suggestions on future research directions. This paper discusses methods for recent rare variant association studies in three categories. The first two categories are for population-based designs, with/without considering the direction of the effects of causal rare variants. In the third category, methods for family-based designs are concluded. .. Read More»
  DOI: 10.4172/2161-0436.1000133

  Abstract PDF