Microbiology, Eldoret, Riftvalley 30100
Kenya
Research Article
Combined Effect of Crude Leaf Extracts of Selected Medicinal Plants against Selected Enteric Bacterial Pathogens and Candida albicans
Author(s): Rachuonyo HO, Ogola PE, Arika WM, Wambani JR, Gatheri GW and Nyamache AKRachuonyo HO, Ogola PE, Arika WM, Wambani JR, Gatheri GW and Nyamache AK
The main aim of the study was to determine the antimicrobial potency of the plant extracts from leaves of Aloe secundiflora, Bulbine frutescens, Tagetes minuta and Vernonia lasiopus when used in combinations. The extracts were used against Gram negative bacteria (Shigella flexineri, Salmonella typhi, Escherichia coli and Enterococcus faecalis), Gram positive bacteria (Staphylococcus aureus) and fungal pathogen Candida albicans by Kirby Bauer method. The combination were determined using the permutation formula of P=N! / (N-R)! Producing six combinations. The combining of the plant extracts from Bulbine frutescens and Vernonia lasiopus with the others showed improved antimicrobial activity especially against Escherichia coli. A decrease in antimicrobial activity was observed when all the plant extracts were used in combinations against Candida albicans. The standard antibiotics used we.. Read More»
DOI:
10.4172/2472-1212.1000110
Journal of Antimicrobial Agents received 444 citations as per Google Scholar report