Pulmonary & Respiratory Medicine

Radostina Vlaeva Cherneva

Publications

• Research Article
  Resistin and Cardiac Remodeling in Patients with Obstructive Sleep Apnea
  Author(s): Radostina Vlaeva Cherneva, Ognian Borisov Georgiev, Daniela Stoichkova Petrova, Emil Ivanov Manov, Radoslav Georgiev Biluykov, Adelina Dimitrova Cakova and Julia Ivanova PetrovaRadostina Vlaeva Cherneva, Ognian Borisov Georgiev, Daniela Stoichkova Petrova, Emil Ivanov Manov, Radoslav Georgiev Biluykov, Adelina Dimitrova Cakova and Julia Ivanova Petrova
  
  Background: Resistin is an adipocytokine, associated with obesity and inflammation. Its exact role in insulin resistance and diabetes is still controversial, but there is now enough data, concerning its direct effects on myocardial cells. The relation between resistin plasma levels with risk of new onset heart failure in humans has been confirmed in several large studies. Materials and methods: Resistin plasma levels were measured in 30 patients with obstructive sleep apnea and mild systolic dysfunction (ejection fraction 45, 7% ± 6, 17%), and compared to fifteen patients with obstructive sleep apnea and normal ejection fraction (ejection fraction 60, 3 ± 6, 3%). The effect of bilevel positive airway pressure therapy was evaluated during a three month follow-up in 19 patients. The dynamics of markers of haemodynamic stress – NT-pro-BNP wa.. Read More»
  DOI: 10.4172/2161-105X.1000186

  Abstract PDF