West Indies
Research Article
Biophysical Characteristics of Melasma Skin Comparing with the Perilesional Normal Skin and its Relation to the Melasma Subtype
Author(s): Rahrovan S, Hasanzadeh H, Khodakarim S and Firooz ARahrovan S, Hasanzadeh H, Khodakarim S and Firooz A
Background: Melasma is a common disorder of hyperpigmentation affecting millions of people worldwide. All the exact pathways to understand the complete pathogenesis of melasma is unknown. Aims: To determine the biophysical characteristics of melasma skin compared to the normal surrounding skin.
Methods: Thirty-six patients with melasma were recruited in this case-control study. The subtype of melasma (epidermal, dermal, or mixed) was determined by Wood lamp examination. The melanin index, erythema index, stratum corneum (SC), hydration, sebum content, transepidermal water loss (TEWL), temperature, friction index, and pH of lesional and perilesional normal skin of patients were measured in standardized temperature and humidity conditions. The epidermal and dermal thickness and dermal echo-density were determined on the same locations. The measurements were compared between lesio.. Read More»
DOI:
10.4172/2376-0427.1000222
Journal of Dermatology and Dermatologic Diseases received 4 citations as per Google Scholar report