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Case Report
Paraneoplastic Cerebellar Degeneration: A Rare but Important Consideration
Author(s): Prithvi Giri, Rakesh Shukla, Vikram V Holla and Vinod Kumar MehtaPrithvi Giri, Rakesh Shukla, Vikram V Holla and Vinod Kumar Mehta
Paraneoplastic cerebellar degeneration is an uncommon autoimmune disorder characterized clinically by progressive, ultimately incapacitating ataxia and pathologically by destruction of cerebellar Purkinje cells, with variable loss of other cell populations. The paraneoplastic cerebellar degeneration can antedate the recognition of malignancy and hence can be a warning sign for occult tumor. We are reporting two cases of paraneoplastic cerebellar degeneration that presented before any evidence of tumor and later developed advanced stage of malignancy not amenable for surgery.
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DOI:
10.4172/2165-7920.1000700
Journal of Clinical Case Reports received 1345 citations as per Google Scholar report