Cancer Science & Therapy

Ramesh Perimi

Publications

• Research Article
  Clinical Studies on Hormonal Status in Breast Cancer and its Impact on Quality of Life (QOL)
  Author(s): Kaiser Jamil, Kalyan Kumar, S. Hajira Fatima, Syed Rabbani, Ravi Kumar and Ramesh PerimiKaiser Jamil, Kalyan Kumar, S. Hajira Fatima, Syed Rabbani, Ravi Kumar and Ramesh Perimi
  
  Breast cancer is a steroid hormone–dependent tumor. Stratification of patients according to hormone (ER/ PR) receptor status and nodal metastasis is of great therapeutic importance. In this investigation, we could enroll 79 pre and post-menopausal breast cancer patients voluntarily. We classified these cases into four categories of the combinations of ER/PR positive, negative and mixed statuses. Their hormone receptor status as determined by immunohistochemistry correlated with therapy regimens like chemotherapy, hormone therapy and QOL responses. We found that in ER+/PR- and ER-/PR- tumors were more frequent in postmenopausal women than ER+/PR+ tumors. The ER+/PR- tumors were larger than ER+/PR+ tumors. In addition, 21.51% of ER+/PR- and 17.72% of ER-/PR- patients had four or more axillary nodes involved with tumors compared to patients with ER+/PR+ tumors (7.59%). Postmenopaus.. Read More»
  

  Abstract PDF