Journal of AIDS & Clinical Research

Rana Jahanban-Esfahlan

Publications

• Review Article
  Nanomagnet-Based Detoxifying Machine: An Alternative/Complementary Approach in HIV therapy
  Author(s): Khaled Seidi, Ali Eatemadi, Behzad Mansoori, Rana Jahanban-Esfahlan and Davoud FarajzadehKhaled Seidi, Ali Eatemadi, Behzad Mansoori, Rana Jahanban-Esfahlan and Davoud Farajzadeh
  
  Although the use of highly active antiretroviral therapy (HAART) hampers HIV-1 replication, it is not yet a cure. The main obstacle to HAART-mediated HIV eradication is the latent reservoir of virally infected cells, which is the source of fast viral rebound in patients that stopped therapy. Patients must therefore have lifelong HAART, which is expensive and in long term the many side effects undermine successful treatment. Attempts to eradicate latent reservoir have focused on reactivating latent proviruses. However, killing the infected cells after virus reactivation, which is pivotal for elimination of the reservoir, has not been addressed. In this paper, we proposed a novel complementary approach, which we have called the “Nanomagnet-Based Detoxifying Machine (NBDM)” and, is able to eliminate the virus load in the bloodstream of the patients. In this regard, our propos.. Read More»
  DOI: 10.4172/2155-6113.1000304

  Abstract PDF