Egypt
Research Article
Endothelial Dysfunction in Pediatric Renal Transplant Recipients
Author(s): Fatina Fadel, Hafez Bazaraa, Rania Hachem, Doaa M Salah and Hesham SafouhFatina Fadel, Hafez Bazaraa, Rania Hachem, Doaa M Salah and Hesham Safouh
Background: Cardiovascular disease is a major cause of morbidity and mortality after kidney transplantation. Endothelial dysfunction was shown to constitute an independent predictor of cardiovascular events. This study aimed at detecting endothelial dysfunction in pediatric renal transplant recipients.
Methods: This was a prospective cohort study of 36 pediatric renal transplant recipients during their first posttransplantation year (transplantation group), 30 patients with end stage renal disease (ESRD) on regular hemodialysis (HD) (dialysis group) and 30 normal subjects (control group). Doppler ultrasound was performed for assessment carotid artery intima-media thickness (IMT) and brachial artery flow-mediated dilatation (FMD).
Results: Carotid artery IMT measurements in the transplantation group (mean ± SD = 0... Read More»
DOI:
10.4172/2161-0991.1000167
Transplantation Technologies & Research received 223 citations as per Google Scholar report