Transplantation Technologies & Research

Rauff-Mortensen Andreas

Publications

• Research Article
  Microdialysis: Reducing the Delay in Detection of Shift in Molecular Composition a Laboratory Study
  Author(s): Rauff-Mortensen Andreas, Kirkegaard Hans and Birke-Sørensen HanneRauff-Mortensen Andreas, Kirkegaard Hans and Birke-Sørensen Hanne
  
  Introduction: Microdialysis is one of the methods used clinically for the detection of ischemia. Although microdialysis is reliable, in most clinical settings there is a delay of 1-2 hours before the information is available. Objective: The aim of this study was to evaluate whether an increase in the Microdialysis per fusion rate from 0.3 to 1.0 or 2.0 μl/min was capable of reducing the delay in the detection of a shift in molecular composition. Methods and material: Microdialysis was performed in a container with 3 catheters per fused with 0.3, 1.0 and 2.0 μl/min. The molecular composition in the container regarding glucose and lactate was initially as follows: CGlucose=6.0 mmol/L and CLactate=2 mmol/L. At T=90 min the composition was changed to CGlucose=1 mmol/L and CLactate=12 mmol/L.&n.. Read More»
  DOI: 10.4172/2161-0991.1000126

  Abstract PDF