Journal of Pharmacognosy & Natural Products

Rauzatul Sakinah

Publications

• Research Article
  Anti-dormant Mycobacterium bovis Produced by Indonesian’s Marine Sponge Xestospongia muta
  Author(s): Guntur Febrian Illahi, Rauzatul Sakinah, Nanda Muhammad Razi, Syarifah Keumala, Khairunnisa and Viqqi KurniandaGuntur Febrian Illahi, Rauzatul Sakinah, Nanda Muhammad Razi, Syarifah Keumala, Khairunnisa and Viqqi Kurnianda
  
  Mycobacterium bovis is the causative agent for tuberculosis disease. This Mycobacterium has an ability to become dormant. Isolation and characterization of bioactive compounds from Indonesian’s Marine Sponge Xestospongia muta, Clathria sp., and Endectyon delaubenfelsi have been done on May 2018. Bioactive compound was isolated based on bioassay-guided separation. The results of Minimum Inhibitory Concentration showed cytotoxic from Xestospongia muta is 0.4 μg/mL, Clathria sp. is 0.5 μg/mL, and Endectyon delaubenfelsi is 0.8 μg/mL. Interpretation of FTIR spectrum showed that the active compound from Xestospongia muta has O-H alcohol functional group at 3435 to 56 cm-1 with the fingerprint region of C-O alcohol functional group at 1342 to 24 cm-1. The C≡N imine functional group was detected at 2365 to 28.. Read More»
  

  Abstract PDF