Nuclear Medicine & Radiation Therapy

RC Karl

Publications

• Research Article
  Post Chemoradiation PET SUV is highly Predictive of Overall Survival in Esophageal Cancer
  Author(s): H Lomas, SE Hoffe, J Weber, TJ Dilling, MD Chuong, K Almhanna, RC Karl, K. Meredith and R ShridharH Lomas, SE Hoffe, J Weber, TJ Dilling, MD Chuong, K Almhanna, RC Karl, K. Meredith and R Shridhar
  
  Purpose: Positron Emission Tomography (PET) scan is a vital tool in the staging, prognosis and response evaluation of gastrointestinal malignancies. The purpose of this study is to determine the prognostic significance of PET standardized uptake values (SUV) in esophageal cancer treated with chemoradiotherapy (CRT). Methods: An IRB approved esophageal cancer database was queried for patients who completed treatment for esophageal cancer with CRT between 2006 and 2010. Patients were included in the analysis if they had nonmetastatic esophageal cancer that completed definitive or preoperative CRT and had pre- and post-CRT PET scans. Patients treated with induction chemotherapy were excluded. The pre-and post-CRT SUV maximum values were obtained. Univariate analysis for overall survival (OS) was performed with Kaplan-Meier and log-rank analysis or hazard ratio model. Multivariate.. Read More»
  DOI: 10.4172/2155-9619.1000125

  Abstract PDF