Journal of Cytology & Histology

Rehab A Rifaai

Publications

• Research Article
  Histopathological and Histochemical Assessment of the Protective Effects of Zinc on Ethanol-Induced Acute Hepatotoxicity in Adult Albino Rats
  Author(s): Ahmed TM Elshennawy, Saadia R Sayed, Entesar A Saber and Rehab A RifaaiAhmed TM Elshennawy, Saadia R Sayed, Entesar A Saber and Rehab A Rifaai
  
  Alcoholic hepatotoxicity is a worldwide major cause of death. The objectives of the present study are to evaluate qualitatively as well as to a less extent quantitatively the protective effects of zinc on acute alcoholic hepatotoxicity. Forty five adult male albino rats were equally divided into three groups. Group I, the ‘control’ one while group II, ‘ethanol-treated’ was received ethanol with a total accumulative dosage of 15 g/kg/36 hours (10 g/kg/day) by three equally divided gavages of 5 g/kg/12 hours each, to simulate acute alcohol intoxication or quadruple bingedrinking among humans. Group III, ‘zinc/ethanol-treated’ was received an intraperitoneal injection of zinc sulfate as 5 mg/kg/day for three days before ethanol administration. Qualitative histological and histochemical parameters were undertaken by using hematoxylin and eosin, iron hem.. Read More»
  DOI: 10.4172/2157-7099.1000321

  Abstract PDF