Tanzania
Research Article
Identification of Differentially Expressed MiRNAs in Appendiceal Mucinous
Cystadenocarcinoma from Mucinous Cystadenoma
Author(s): Richard Licheng Wu, Shadan Ali, Fazlul H Sarkar and Rafic BeydounRichard Licheng Wu, Shadan Ali, Fazlul H Sarkar and Rafic Beydoun
Objective: Mucinous cystadenocarcinoma of appendix is a rare entity. To differentiated mucinous cystadenocarcinoma from mucinous cystadenoma is very challenging and depends on establishing the presence of malignant cells in the appendix wall. The invasion may be very difficult to assess in some cases, especially in early stages of the disease, which could have devastating prognostic effects on patients. Therefore, it is necessary to develop an ancillary test that can differentiate the mucinous cystadenocarcinoma from mucinous cystadenoma. So far, there is no report available about the role of differentially expressed miRNAs in the diagnosis of appendiceal mucinous cystadenocarcinoma.
Materials and Methods: Six confirmed mucinous appendiceal cystadenocarcinoma and twelve mucinous appendiceal cystadenoma cases were selected. The total RNAs were .. Read More»
DOI:
10.4172/1948-5956.1000371
Cancer Science & Therapy received 5282 citations as per Google Scholar report