Nuclear Medicine & Radiation Therapy

Richard M Fleming

Publications

• Research Article
  Both Percent Diameter Stenosis (%DS) and Coronary Flow Reserve (CFR) can be Derived Directly from Myocardial Perfusion Imaging (MPI) using FMTVDM^©℗ and Measurement of Isotope Redistribution
  Author(s): Richard M Fleming, Matthew R Fleming, Tapan Chaudhuri, Andrew McKusick, William C Dooley and Charles GloverRichard M Fleming, Matthew R Fleming, Tapan Chaudhuri, Andrew McKusick, William C Dooley and Charles Glover
  
  Background: Scientifically published studies have demonstrated that all isotopes, including Sestamibi redistribute. Measurement of this redistribution using FMTVDM©â?? provides an accurate method for determining wash-in and washout. Methods: Using FMTVDM©â?? 1040 human coronary arteries were studied to determine their wash-in and washout redistribution measured on a pixel-by-pixel basis. From FMTVDM©â?? the percent diameter stenosis (%DS) for each artery was determined. This %DS was then used to calculate coronary flow reserve (Calculated SFR) using a proprietary quadratic equation (QCFR©, FCFR©) previously derived from quantitative coronary arteriography (QCA) measurements. These calculated CFR values were then compared with the actual measured CFR obtained directly from QCA. Results: The result.. Read More»
  DOI: 10.4172/2155-9619.1000353

  Abstract PDF