Nuclear Medicine & Radiation Therapy

Robert L Foote

Publications

• Research Article
  Long-term Results of a Pilot Study Comparing FLT-PET and FDG-PET in the Evaluation of Response to Treatment in Advanced Head and Neck and Esophageal Malignancies
  Author(s): Ryan S Youland, Val J Lowe, Robert L Foote, Deanna H Pafundi, Scott H Okuno, Robert C Miller, Steven R Alberts, Debra H Brinkmann and Jann N SarkariaRyan S Youland, Val J Lowe, Robert L Foote, Deanna H Pafundi, Scott H Okuno, Robert C Miller, Steven R Alberts, Debra H Brinkmann and Jann N Sarkaria
  
  Objective: We prospectively compared FDG-PET and FLT-PET in assessing patient responses to induction cetuximab and/or chemoradiotherapy (CRT) for advanced head and neck squamous cell carcinoma (HNSCC) and esophageal cancer (EC). Methods: Sixteen patients were enrolled, 9 with HNSCC and 7 with EC. FDG-PET and FLT-PET scans were performed at baseline and two weeks into chemoradiotherapy (CRT) for patients with EC. Patients with HNSCC received two weeks of induction chemotherapy along with post-induction PET scans prior to starting CRT in addition to the baseline and intra-chemoradiotherapy PET scans. Changes in SUVmax and total lesion glycolysis/ proliferation (TLG/TLP) were compared with baseline. Results: Median follow-up for living patients was 6.0 years. Median overall survival (OS) was 3.3 years and progression-.. Read More»
  DOI: 10.4172/2155-9619.1000328

  Abstract PDF