Brazil
Case Report
Association between Neurofibromatosis Type I and Central Giant Cell Lesion: Case Report
Author(s): Monyque Cunha Trindade, Fernando Melhem Elias, Rodrigo Chenu Migliolo, Nathalia Cayuela Nogueira and Flávio Welington da Silva FerrazMonyque Cunha Trindade, Fernando Melhem Elias, Rodrigo Chenu Migliolo, Nathalia Cayuela Nogueira and Flávio Welington da Silva Ferraz
Neurofibromatosis type I (NF1), or Von Recklinghausen disease, is characterized by café-au-lait spots and neurofibromas of the skin, bone defects, iris hamartomas (Lisch nodules) and tumors in the central nervous system. The central giant cell lesion (CGCL) is a non-neoplastic entity, intra-osseous, radiolucent, uni or multilocular, well-defined edges, and it can change the position of the teeth, but rarely causes resorption of them. The association between CGCL and NF1 has been described in the literature. Patient C.R.P, 42 years old, female, who has NF1 attended the service presenting asymptomatic swelling in the anterior maxilla and discrete painless intraoral bulge in the anterior mandible with approximate evolution of one year. Incisional biopsy was performed, and the result was CGCL. The patient didn’t have hyperparathyroidism. Treatment consisted of curettage of th.. Read More»
DOI:
10.4172/2376-0427.1000161
Journal of Dermatology and Dermatologic Diseases received 4 citations as per Google Scholar report