Malaria Control & Elimination

Roger Clément Kouly Tine

Publications

• Research Article
  Effect of Seasonal Malaria Chemoprevention (SMC) with SulfadoxinePyrimethamine (SP) and Amodiaquine (AQ) on the Acquisition of antiAMA1 and anti-MSP1_42 Antibodies among Children under 10 Years Living in the Southern part of Senegal (Velingara)
  Author(s): Khadime Sylla, Roger Clément Kouly Tine, Doudou Sow, Magatte NDiaye, Aissatou Sarr, Marie Louise Tshibola Mbuyi, Ibrahima Diouf, Jean Louis Abdourahim Ndiaye, Daouda NDiaye, Oumar Gaye and Babacar FayeKhadime Sylla, Roger Clément Kouly Tine, Doudou Sow, Magatte NDiaye, Aissatou Sarr, Marie Louise Tshibola Mbuyi, Ibrahima Diouf, Jean Louis Abdourahim Ndiaye, Daouda NDiaye, Oumar Gaye and Babacar Faye
  
  Background: In developing countries, malaria is still a leading cause of morbidity and mortality and children are the most affected individuals. In order to strengthen malaria control, new intervention such as Seasonal Malaria Chemoprevention (SMC) has been developed. This strategy is very effective in preventing malaria clinical episodes but its effect on children’s immunity is not well documented. This study aimed to evaluate the effects of SMC on the acquisition of anti-AMA1 and anti-MSP1_42 antibodies among children fewer than 10 years living in the southern part of Senegal (Velingara). Patients and methods: The study was nested in a cluster randomized trial assessing the impact of SMC with a single dose of Sulfadoxine-Pyrimethamine (SP) and 3 doses of Amodiaquine (AQ). Two cross-sectional surveys were carried out (October 2010) and (September 2011) to assess the effect of S.. Read More»
  

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