Research Article
In vitro Sensitivity to Fluconazole through Vitek II Systems, of Strains of Candida Spp. In Patients with Oropharyngeal Candidiasis and HIV/AIDS
Author(s): Verónica Gaona-Flores, Roberto Quiróz- Guzmán, Rosa María Cervantes-Tovar, Enrique Alcalá-Martínez, María Isabel Sandoval-Arrieta and Luz Arcelia Campos-NavarroVerónica Gaona-Flores, Roberto Quiróz- Guzmán, Rosa María Cervantes-Tovar, Enrique Alcalá-Martínez, María Isabel Sandoval-Arrieta and Luz Arcelia Campos-Navarro
Background: Candida albicans is a commensal fungus of the mucosa in humans that may become an opportunistic pathogen causing recurrent infections in immunocompromised hosts. In individuals with HIV/AIDS, Histatin-5 levels are significantly reduced, causing oropharyngeal candidiasis to become a pathological process. Clinical and in vitro resistance to azoles is common whether by selection or acquisition of Candida-resistant strains. In 2008, the Clinical and Laboratory Standards Institute (CLSI) defined the cutoff point for active agents against the isolates of Candida species. The objective of this study was to determine the frequency of fungal isolates of C. albicans through VITEK II system and their susceptibility pattern in patients with HIV/AIDS and oropharyngeal candidiasis treated at the Hospital for Infectious Diseases in Mexico City.
Methods: From June 2011-December 20.. Read More»
DOI:
10.4172/2155-6113.1000230
Journal of AIDS & Clinical Research received 5061 citations as per Google Scholar report