Journal of AIDS & Clinical Research

Rui A Ferriani

Publications

• Research Article
  Effect of Coadministration of Etonogestrel Implant and Antiretroviral Therapies Containing Efavirenz or Lopinavir/Ritonavir on the Metabolism of Women Living with HIV/AIDS
  Author(s): Tatiana R Rocha Prandini, Maria Valeria Bahamondes, Milena B Brito, Eliana Amaral, Luis Bahamondes, Geraldo Duarte, Silvana M Quintana, Rui A Ferriani and Carolina Sales VieiraTatiana R Rocha Prandini, Maria Valeria Bahamondes, Milena B Brito, Eliana Amaral, Luis Bahamondes, Geraldo Duarte, Silvana M Quintana, Rui A Ferriani and Carolina Sales Vieira
  
  Background: Concomitant use of antiretroviral therapy (ART) and hormonal contraceptives should be safe for women while maintaining medication efficacy without causing significant immunological or metabolic changes. However, the metabolic effect of the concomitant use of etonogestrel (ENG)-releasing implant and commonly used ARTs is not known. Objective: To evaluate the effect of coadministration of ENG-releasing implant and ARTs containing lopinavir/ ritonavir or efavirenz on the metabolic parameters of women living with human immunodeficiency virus (HIV) infection/ acquired immune deficiency syndrome (AIDS). Methods: This is an open, prospective, non-randomized exploratory study. Forty-five women who sought to receive the ENG contraceptive implant were selected, including 15 non-ART users, 15 zidovudine/lamivudine (AZT/3TC)+lopinavir/ritonavir users and 15 AZT/3TC+efavirenz users f.. Read More»
  DOI: 10.4172/2155-6113.1000674

  Abstract PDF