Journal of AIDS & Clinical Research

Russell B Van Dyke

Publications

• Research Article
  Outcomes of Infants Born to HIV-Infected Women Identified by Rapid HIV Testing Late in Pregnancy or at Delivery: The MIRIAD Study
  Author(s): Russell B Van Dyke, Susan P Danner, Sarah Chrestman, Patricia Kissinger, Steven Nesheim, Angela M Amedee, Gwendolyn Scott, Mardge H Cohen, Elaine J Abrams, Denise J Jamieson, Mary Glenn Fowler, Athena P Kourtis, Marc Bulterys and for the MIRIAD Study GroupRussell B Van Dyke, Susan P Danner, Sarah Chrestman, Patricia Kissinger, Steven Nesheim, Angela M Amedee, Gwendolyn Scott, Mardge H Cohen, Elaine J Abrams, Denise J Jamieson, Mary Glenn Fowler, Athena P Kourtis, Marc Bulterys and for the MIRIAD Study Group
  
  Background: Rapid HIV testing late in pregnancy or at delivery provides a final opportunity (among non-breastfeeding mothers) to identify HIV-infected women and initiate antiretroviral drugs to prevent mother-to-child transmission. Methods: MIRIAD was a CDC-funded study conducted from 2001-2005 at 17 hospitals in 6 US cities. Eligible women had undocumented HIV status when presenting in labor or after 34 weeks gestation and not in labor. We performed both rapid HIV-1 antibody testing of blood and conventional enzyme immunoassay with Western blot confirmation. Women and infants were managed according to the local standard of care. Infant infection status was determined by HIV DNA or RNA PCR testing. Results: Fifty-one infants (1 pair of twins) were born to 50 women. Among those with data available, 17% of women received prenatal antiretroviral and 7.. Read More»
  DOI: 10.4172/2155-6113.1000484

  Abstract PDF