Molecular Biomarkers & Diagnosis

Rypko Beukema

Publications

• Research Article
  Serial N-Terminal Pro Brain Natriuretic Peptide Assessments in Predicting New-Onset Atrial Fibrillation in ST Elevation Myocardial Infarction Patients who Undergo Primary Percutaneous Coronary Intervention
  Author(s): Emel Parlak, Pim Gal, Dirk A.A.M. Schellings, Rypko Beukema, Ahmet Adiyaman, Jurriën ten Berg, Arnoud W.J. van ’t Hof and Arif ElvanEmel Parlak, Pim Gal, Dirk A.A.M. Schellings, Rypko Beukema, Ahmet Adiyaman, Jurriën ten Berg, Arnoud W.J. van ’t Hof and Arif Elvan
  
  Background: N-terminal pro-Brain Natriuretic Peptide(NT-proBNP)is associated with atrial fibrillation(AF) in the setting of acute ST-elevation myocardial infarction (STEMI), and the present study was aimed at assessing the temporal association between NT-proBNP and incident AF. Methods: 830 patients enrolled in On-TIME II were included. NT-proBNP was assessed at baseline, 24 h and 72 h after admission for STEMI. Patients with new-onset AF <30 days after STEMI were divided among 3 subgroups: AF on admission, AF 24-72 h after admission and AF >72 h after admission. NT-proBNP serum levels at the three assessment intervals was used to predict the timing of AF with a receiver-operator characteristic, and a binary logistic model was created to predict the AF at the various timings. Results: Mean age was 62 ±.. Read More»
  DOI: 10.4172/2155-9929.1000268

  Abstract PDF