Journal of Tissue Science and Engineering

SA Clarke

Publications

• Research Article
  An in vitro Study to Assess the Potential of a Unique Micro porous Algal Derived Cap Bone Void Filler in Comparison with Clinically-Used Bone Void Fillers
  Author(s): PJ Walsh, SA Clarke, J Nelson, CA. Maggs, GM Walker and FJ BuchananPJ Walsh, SA Clarke, J Nelson, CA. Maggs, GM Walker and FJ Buchanan
  
  Macroporosity(>100?m) in bone void fillers is a known prerequisite for tissue regeneration, but recent literature has highlighted the added benefit of microporosity(0.5 - 10?m). The aim of this study was to compare the in vitro performances of a novel interconnective microporous hydroxyapatite (HA) derived from red algae to four clinically available macroporous calcium phosphate (CaP) bone void fillers. The use of algae as a starting material for this novel void filler overcomes the issue of sustainability, which overshadows continued use of scleractinian coral in the production of some commercially available materials, namely Pro-Osteon TM and Bio-Coral ® . This study investigated the physicochemical properties of each bone voidfiller material using x-ray diffraction, fourier transform infrared spectroscopy, inductive coupled plasma, and nitrogen gas absorption and mercury por.. Read More»
  DOI: 10.4172/2157-7552.S1-002

  Abstract PDF