Cardiovascular Diseases & Diagnosis

Sachin Kumar Amruthlal Jain

Publications

• Research Article
  Degree of Beta-Blockade and Outcomes in Patients with Acute Coronary Syndrome
  Author(s): Sachin Kumar Amruthlal Jain, Timothy R. Larsen DO, Charlotte Wiemann, Patrick Alexander, Michael Shaw, Peter A McCullough and Shukri DavidSachin Kumar Amruthlal Jain, Timothy R. Larsen DO, Charlotte Wiemann, Patrick Alexander, Michael Shaw, Peter A McCullough and Shukri David
  
  Objective: We sought to determine if the outcome benefit of beta blockade in the ACS population is associated with baseline HR, discharge HR, or a reduction in HR. Background: ACC guidelines recommend a resting HR goal of 50 to 60 bpm in ACS patients. This recommendation is not based on study outcomes, but rather on expert opinion. Evidence-based clinical trials investigating ideal target heart rate of beta blocker (BB) therapy in the ACS population are lacking. Methods: A retrospective analysis was performed of all ACS patients who underwent coronary angiography (with or without percutaneous coronary intervention) at Providence Hospital from September 2006 to August 2011 excluding patients with any contraindication to BB therapy. Discharge HR was used as the predictor variable for outcomes in thes.. Read More»
  DOI: 10.4172/2329-9517.1000150

  Abstract PDF