Molecular Biomarkers & Diagnosis

Samah Abdelrahman Elshweikh

Publications

• Research Article
  Association between Angiotensin Converting Enzyme Insertion/Deletion Polymorphism and Soluble Receptor of Advanced Glycation End Products in Type 2 Diabetic Patients with and without Microalbuminuria
  Author(s): Hanaa Hibishy Gaballah, Rasha Ahmed Gaber and Samah Abdelrahman ElshweikhHanaa Hibishy Gaballah, Rasha Ahmed Gaber and Samah Abdelrahman Elshweikh
  
  Aims/Introduction: Studies on the association between a deletion variant of the angiotensin-converting enzyme (ACE) gene and diabetic microalbuminuria and its impact on AGE/RAGE system remain inconclusive. Therefore, we aimed to study the association between ACE I/D polymorphism and the circulating levels of sRAGE (soluble receptor for advanced glycation end-products (sRAGE), pentosidine and advanced oxidation protein products (AOPPs) in type 2 diabetic patients with and without microalbuminuria. Subjects and methods: ACE I/D polymorphism was analyzed using the amplified fragment length polymorphism Polymerase Chain Reaction method (AFLP). Circulating levels of sRAGE and pentosidine were assessed using enzyme linked immunosorbent assay, while AOPPs were assessed photometrically. Results: within the diabetic normoal.. Read More»
  DOI: 10.4172/2155-9929.1000203

  Abstract PDF