Molecular Biomarkers & Diagnosis

Sameer H. Fatani

Publications

• Research Article
  Correlation between Serum Anti-Apoptotic Bcl-2 Level and its Immunohistochemical Expression in Relation to Apoptosis in Gastric Cancer
  Author(s): Sameer H. Fatani, Mohammed H. Mukhtar, Abeer S. Ali, Hoda M. El- Emshaty and Wesam A. NasifSameer H. Fatani, Mohammed H. Mukhtar, Abeer S. Ali, Hoda M. El- Emshaty and Wesam A. Nasif
  
  Introduction: Gastric cancer (GC) remains a major public health problem worldwide being the third commonest cause of cancer death worldwide. Many recent studies focus on the immunohistochemical evaluation of Bcl-2 expression and its serum expression and its prognostic significance in gastric cancer each one separately. We conducted our study to determine the correlation between serum Bcl-2 antigen and gastric carcinoma, to investigate whether serum Bcl-2 concentrations can be used as marker for immunohistochemical determination of Bcl-2 alterations in gastric cancer patients and examine the association between its expression and other clinicopathological parameters. Methods: Our study conducted in Forty-five consecutive patients with gastric cancer underwent gastrectomy in Mansoura Gastroenterology Center. ELISA was used for the estimation o.. Read More»
  DOI: 10.4172/2155-9929.1000248

  Abstract PDF