Professor of Pediatric Infectious Diseases, Research Center of Pediatric Infectious Diseases,
4th floor Hazrat Rasul Hospital, Niayesh Street, Satarkhan Avenue, Tehran, 14455
Iran, Islamic Republic of
Research Article
Associations Between Antibodies Against the Endothelial Cell and T.gondii; Cytomegalovirus in Serum of Children with Cochlear Implant Surgery
Author(s): Samileh Noorbakhsh, Mohammad Farhadi, Ahamad Daneshi, Azardokht Tabatabaei, Emam H jomeh and Yaser GhavamiSamileh Noorbakhsh, Mohammad Farhadi, Ahamad Daneshi, Azardokht Tabatabaei, Emam H jomeh and Yaser Ghavami
Background: Cytomegalovirus (CMV) and T. gondii are two common causes of SNHL (Sensorineural hearing loss) in Iranian children. Immune-mediated vascular damage induced by endothelial cell antibodies may have a prominent role in sensorineural hearing loss. Objectives: To determine the serum CMV and T. gondii antibodies against endothelial cell in children with profound SNHL and cochlear implant surgery.
Materials & Methods: A cross sectional study was performed on 76 cases with severe SNHL (mean age 32 ± 30.6 months) at cochlear implant ward of Rasoul hospital, Tehran Iran (2008-2010). The titers of antibodies against endothelial cell (Indirect immunofluorescence assay); were determined in sera of 66 cases. Specific antibodies (IgG & IgM) against T. gondi, CMV (Enzyme linked immunosorbent assay) determined in Idiopathic SNHL cases.
Results: Idiopathic typ.. Read More»
DOI:
10.4172/2155-6113.1000197
Journal of AIDS & Clinical Research received 5061 citations as per Google Scholar report
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