Research Center of Pediatric Infectious Diseases,
4th floor Rasoul Hospital, Niayesh Street, Satarkhan Avenue, Tehran, 14455
Iran, Islamic Republic of
Research Article
Role of H. pylori Infection (Serology, PCR) in Chronic Idiopathic Thrombocytopenic Purpura in an Endemic Country: A Case Control Study, Tehran, IRAN
Author(s): Mohammad Faranoush, Samileh Noorbakhsh, Azim Mehrvar and zardokht TabatabaeMohammad Faranoush, Samileh Noorbakhsh, Azim Mehrvar and zardokht Tabatabae
Background: A practical guideline for detection and managements of some common infectious agents in cases with chronic ITP (Idiopathic Thrombocytopenic Purpura) is so important. Objectives: to investigate the role of H. pylori infection in children with chronic ITP in an endemic area. Materials and methods: A case control study done in pediatric ward Rasul Hospital, Tehran, Iran (2009-2010). 51 chronic ITP cases and 25 controls were assessed. H. pylori IgG & IgA ELISA (LDN -Germany) assesses in all cases and controls. All cases undergoing Bone Marrow Aspiration. H. pylori -PCR evaluated (QIAquickP® QIAGEN; Germany). P-value <0.05 was considered statistically significant. Results: cases were between 1- 20 years (mean 13.3.5 ± 7.6 y). Platelet count varied between 5000-1330000 (mean 63621 ± 37369.9) Positive H. pylori- IgA observed in 70% (36/51) of cases and 4%.. Read More»
DOI:
10.4172/2155-6113.1000209
Journal of AIDS & Clinical Research received 5264 citations as per Google Scholar report
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