Journal of AIDS & Clinical Research

Samuel OM Manda

Publications

• Research Article
  Risk of Death among HIV Co-Infected Multidrug Resistant Tuberculosis Patients, Compared To Mortality in the General Population of South Africa
  Author(s): Samuel OM Manda, Lieketseng J Masenyetse, Joey L Lancaster and Martie L van der WaltSamuel OM Manda, Lieketseng J Masenyetse, Joey L Lancaster and Martie L van der Walt
  
  Background: Even though highly effective drugs are available in South Africa, multidrug resistant tuberculosis (MDR-TB) patients with HIV infection have higher mortality compared to HIV-uninfected MDR-TB patients. This trend has been observed in similar countries with high HIV prevalence. This study sought to ermine excess mortality attributable to HIV among MDR-TB patients in South Africa using relative survival methods. Methods: Data available were from a cohort of 2079 MDR-TB patients enrolled in a Standardized Programmatic Management of MDR-TB from 2000 to 2004 in South Africa. A Poisson-based model adjusted for age, gender, year of diagnosis, TB history, and resistance to ethambutol, anti-TB injectable drugs and fluoroquinolones antibiotics was constructed to assess the excess mortality among HIV co-infected MDR-TB patients. Excess hazard ratios (EHRs) were used to descri.. Read More»
  DOI: 10.4172/2155-6113.S3-007

  Abstract PDF