India
Research Article
Reproductive Outcomes in 101 Couples with Balanced Chromosomal
Rearrangements
Author(s): Dnyandeo Chopade, Suresh Gangane, Sandesh Chopade and Harish HardeDnyandeo Chopade, Suresh Gangane, Sandesh Chopade and Harish Harde
Background: There are very few studies on reproductive outcomes in couples with balanced chromosomal translocations. Findings of such studies can shed light on the possible future outcomes and help in genetic counselling. Objectives: The overall objectives of this study were to report the various chromosomal balanced rearrangements in couples with history of bad reproductive history, to analyse the reproductive outcomes prior to the evaluation and to compare the chromosomal findings with the similar available data from literature.
Methods: Reproductive history of couples identified with balanced chromosomal translocations at Genetic Health and Research Centre, Nashik was studied retrospectively, and the various pregnancy outcomes were tabulated and compared with the available literature data.
Results: Out of 1580 couples investigated for chromosomal abnormalities for the various indica.. Read More»
DOI:
10.4172/2161-0436.1000150
Human Genetics & Embryology received 309 citations as per Google Scholar report