Pulmonary & Respiratory Medicine

Saraphine N Nebere

Publications

• Review Article
  Immunological Interactions of Tuberculosis with Drugs and Substance Use: A Systematic Review and Update
  Author(s): Nathan G Kiboi, Saraphine N Nebere and Joseph K KaranjaNathan G Kiboi, Saraphine N Nebere and Joseph K Karanja
  
  Background: Illicit drug and substance use exacerbates tuberculosis (TB) pandemic and complicates management of the disease. Cytokines play a crucial role in TB infection, and recreational drugs of abuse present a confounder in the understanding of immunology of TB. Therefore, this review presents an updated summary describing the immunological link between illicit drug use and TB. Methods: Information was obtained from previous research findings via Medline search (1990-2015) using the headings tuberculosis, drug interactions, cytokine alterations, prevalence of TB and illicit drug use. In addition, Google scholarly articles and PubMed citations were included in our search. Discussion: Recreational drug induced immunosuppression hastens TB progression among habitual substance users. Additionally, substance consumption in the context of TB infectio.. Read More»
  DOI: 10.4172/2161-105X.1000326

  Abstract PDF