Journal of Cytology & Histology

Sayed Mahmoud A

Publications

• Research Article
  Bone Marrow Derived Mesenchymal Stem Cell Therapy in Induced Acute Renal Injury in Adult Male Albino Rats
  Author(s): Abd Elwahab SA, Hussein Ali A, Sayed Mahmoud A, Fathy Ahmed A and Reda SolimanAbd Elwahab SA, Hussein Ali A, Sayed Mahmoud A, Fathy Ahmed A and Reda Soliman
  
  Background and objectives: Acute renal injury (ARI) is a serious clinical problem without established regimen for treatment. Mesenchymal stem cells (MSCs) are undifferentiated cells that can differentiate and give rise to other cell types. The aim of the present work is to study the possible therapeutic role of MSCs in the treatment of the deleterious changes occurred in renal cortex and medulla of adult male albino rat model of ischemia/reperfusion (I/R) ARI. Material and methods: Forty adult male albino rats were used in this study. Animals were divided into four groups, 10 animals for each group. Group I is control sham-operated group. Three experimental groups were all subjected to I/R injury by clamping both renal pedicles for 40 min. These animals were further divided into three subgroups. Group II is non-MSC treated group. Group III (MSC treated group (local injection)): I/R an.. Read More»
  DOI: 10.4172/2157-7099.1000451

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