Molecular Biomarkers & Diagnosis

Schaalan M

Publications

• Research Article
  Urinary Iodine in Egyptian Patients with Thalassemia Major: A Focus on its Potential Contributing Impact on Consequent Hypothyroidism
  Author(s): El Beshlawy A, Fawaz L, Hamdy M, Kamel AK, Mohamed W, Sabry A and Schaalan MEl Beshlawy A, Fawaz L, Hamdy M, Kamel AK, Mohamed W, Sabry A and Schaalan M
  
  Background: Primary hypothyroidism is one of the most frequent endocrine complications observed in patients suffering from thalassemia where iodine deficiency is a major contributing factor. We aim at assessing the iodine status in multitransfused pediatrics with thalassemia major, compliant to iron chelation, to evaluate its contributing role to the occurring hypothyroidism for the potential future replacement therapy. Procedure: Sixty young thalassemia patients (31 males, 29 females; aged 14.4 ± 3.83 years) were randomly selected from the hematology clinic of the Children’s Hospital, Cairo University, added to 36 age and sex matched control subjects. Results: The study revealed a highly significant difference in urinary iodine, FT3, FT4 and TSH between the thalassemic group and their controls (P<0.001)... Read More»
  DOI: 10.4172/2155-9929.1000211

  Abstract PDF