Journal of Diabetic Complications & Medicine

Sebastjan Merlo

Publications

• Research Article
  Polymorphisms rs699 and rs4762 of the Angiotensinogen Gene and Progression of Carotid Atherosclerosis in Patients with Type 2 Diabetes Mellitus
  Author(s): Sebastjan Merlo, Jovana Nikolajević Starcević, Sara Mankoč, Marija Santl Letonja, Andreja Cokan Vujkovac, Peter Kruzliak and Daniel PetrovičSebastjan Merlo, Jovana Nikolajević Starcević, Sara Mankoč, Marija Santl Letonja, Andreja Cokan Vujkovac, Peter Kruzliak and Daniel Petrovič
  
  Background: The aim of the study was to investigate the association between two polymorphisms of the angiotensinogen (AGT) gene (rs699 and rs4762) and subclinical markers of carotid atherosclerosis in subjects with type 2 diabetes mellitus (T2DM). Patients and methods: In this cross-sectional study 599 subjects with T2DM and 200 subjects without T2DM (control group) were enrolled. The CIMT and plaque characteristics (presence/absence and plaque thickness) on both the near and the far walls in the common carotid artery, bulb and internal carotid arteries, bilaterally were assessed ultrasonographically. After several years (3.8 ± 0.5 years), patients were re-assessed and changes in subclinical markers of carotid atherosclerosis were calculated. Polymorphisms rs699 and rs4762 of the AGT gene were genotyp.. Read More»
  DOI: 10.4172/2475-3211.1000107

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