Turks and Caicos Islands
Research Article
Treatment of Steroid and Cyclophosphamide-Resistant Nephrotic Syndrome with Mycophenolate Mofetil and High Dose Dexamethasone (DEX)
Author(s): Sevgi Mir, Seçil Conkar, Betül Sözeri, Kadriye Özdemir and İpek Kaplan BulutSevgi Mir, Seçil Conkar, Betül Sözeri, Kadriye Özdemir and İpek Kaplan Bulut
Background: Clinicians often face with therapeutic challenges during the treatment of children with steroidresistant nephrotic syndrome (SRNS). The management of SRNS is primarily aimed at decreasing proteinuria and inducing remission. Mycophenolate mofetil (MMF) in combination with steroids is known to have some efficacy in the management of SRNS. The aim of this study is to evaluate the outcome of MMF/DEX therapy regimen.
Material and methods: We reported a prospectively longitudinal clinical series of patients with SRNS, all of whom have been treated with Mycophenolate mofetil and oral dexamethasone (DEX). We enrolled 29 children who were previously treated with steroid and cyclophosphamide at Ege University, Children’s Hospital. Treatment with MMF/DEX was administered for up to 52 .. Read More»
DOI:
10.4172/2161-0959.1000257
Journal of Nephrology & Therapeutics received 784 citations as per Google Scholar report