Neurological Disorders

Senanayake Mudiyanselage Rathnasiri Bandara

Publications

• Review Article
  Migraine and Neurological Disorders Comorbidity-Consideration of Sinus Hypoxic Nitric Oxide Theory for Migraine
  Author(s): Senanayake Mudiyanselage Rathnasiri Bandara, Jayarathna DGAI, Sampath Thenakoon and Kithsiri Jayanath SenananayakaSenanayake Mudiyanselage Rathnasiri Bandara, Jayarathna DGAI, Sampath Thenakoon and Kithsiri Jayanath Senananayaka
  
  Migraine is an extremely common disorder and has co morbidity with many neurological illnesses. After reviewing the neurophysiological and biochemical basis of the research findings and hypotheses of migraine and other neurological disorders I present to the best of my knowledge the first para nasal sinus nitric oxide mediated neurobiophysiological explanation for many neurological disorders. The etiology of neurological illnesses is mainly due to neurotransmitter imbalance, neurodegenerative changes acute and chronic inflammation, effects of hypo and hyper endothelial and neuronal NO levels and genetic predisposition. According to this para nasal sinus nitric oxide based description those effects are mainly brought on by the sinorhinogenic impulse distribution of the central nervous system except genetic predisposition. Moreover, avoidance of the central neuronal influence and stress.. Read More»
  DOI: 10.4172/2329-6895.1000175

  Abstract PDF