Journal of Nephrology & Therapeutics

Serkan Demircan

Publications

• Research Article
  Acute Renal Failure and Thiol-Disulfide Homeostasis
  Author(s): Yavuz Otal, Serkan Demircan, Alp Şener, Murat Alışık, Fatih Tanrıverdi, F Güllü Ercan Haydar, Ayhan Özhasenekler and Özcan ErelYavuz Otal, Serkan Demircan, Alp Şener, Murat Alışık, Fatih Tanrıverdi, F Güllü Ercan Haydar, Ayhan Özhasenekler and Özcan Erel
  
  Aims: Investigating the thiol-disulphide balance in the patients with acute renal failure and evaluating the potential of using tGFR (thiol based GFR) index as a new parameter, alternative to the parameter called estimated Glomerular Filtration Rate (eGFR). Study design: The serum thiol-disulphide levels in the predialysis and postdialysis blood samples of 42 patients diagnosed with acute renal failure in the emergency department and hemodialyzed right after were measured through the novel method. Methods: The acute renal failure was detected through the clinical and laboratory findings, and a hemodialysis procedure was performed. The obtained results were statistically evaluated. While eGFR (ml/min/1.73 m2) values were being calculated, MDRD (Modification of Diet in Renal Disease) formula was used. To calculate tGFR as an alternative to eGFR, .. Read More»
  DOI: 10.4172/2161-0959.1000312

  Abstract PDF