Journal of Cytology & Histology

Serrano L

Publications

• Research Article
  Squamous Cell Atypia Suggesting High-grade Lesions: Correlation of Morphological Data, HPV Test Results and Follow-up
  Author(s): Alameda F, Hernández E, Del Amo E, Bellosillo B, Serrano L and Carreras RAlameda F, Hernández E, Del Amo E, Bellosillo B, Serrano L and Carreras R
  
  Background: Squamous cell atypia suggesting high-grade lesion (ASCH) is a cytological lesion, related to a high-grade lesion. Guidelines recommend performing a colposcopy in these cases, without HPV testing. Objective: Here we sought to determine the value of the HPV test in ASCH cases and to correlate morphological data, the HPV test results, and the follow-up. Methods: Ninety-six patients were diagnosed with ASCH using liquid-based cytology (Thin-Prep®). Hybrid Capture II was the HPV test used. The patients were followed up for 6 to 48 months (mean 24 months). The following cytological data were included: isolated cells; dyskeratosis; hyperchromasia; coarse chromatin; nuclear membrane irregularity; 3D alterations; and molding. Results: The mean age of the patients was 37 years (range 15-78)... Read More»
  DOI: 10.4172/2157-7099.1000396

  Abstract PDF