Neurological Disorders

Sharan P

Publications

• Review Article
  Anti- NMDA Receptor Antibody Encephalitis: - A Review of Nine Patients with Clinical Presentation, Investigations, Treatment and Outcome in Singapore
  Author(s): Sachdeva P, Rohit L, Sharan P, Prakash K, Yip CW and See SJSachdeva P, Rohit L, Sharan P, Prakash K, Yip CW and See SJ
  
  Objective: To report on epidemiology, clinical and laboratory features of patients diagnosed with anti-N-methyl-Daspartate receptor (NMDAR) encephalitis admitted to Singapore general hospital over the period of four years. This is the first study for the local population. Introduction: Anti –NMDA receptor encephalitis is a severe form of encephalitis that associates with antibodies against NMDA receptors resulting in a neuropsychiatric syndrome. It has been considered as a Paraneoplastic syndrome. Methods: Nine patients (6 female and 3 male) admitted to neurology unit from March 2010 to Oct 2013 were studied retrospectively. Diagnosis of anti-NMDA receptor antibody encephalitis was based on encephalitis plus positive CSF serology. Result: Younger age group affected more (range 16 to 65 years). Clinical presentation usually involves the triad of psychotic (100%); seizures (66%) a.. Read More»
  DOI: 10.4172/2329-6895.1000297

  Abstract PDF