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Pharmaceutical Regulatory Affairs: Open Access

ISSN: 2167-7689

Open Access

Sharath Reddy B

Centre of Pharmaceutical Sciences,
Hyderabad, Telangana
India

Publications
  • Research Article
    Formulation and In-vitro Evaluation of Sumatriptan Succinate Bilayer Tablets
    Author(s): Sharath Reddy B, Sunitha Reddy M and Fazal Ul Haq SMSharath Reddy B, Sunitha Reddy M and Fazal Ul Haq SM

    Bilayer tablet is one of the great advanced technologies which contain two different layered formulations with one layer of drug provides immediate release and the other as sustained. Sumatriptan succinate is a triptans class of drug used to treat migraine headaches, which acts selectively at 5-HT1B/1D receptors. The objective is to formulate and evaluate the bilayer tablets of sumatriptan succinate of dose 50 mg. In this case immediate release layer is formulated using sodium starch glycolate, crospovidone and croscarmellose sodium as Super-Disintegrants, Sustained release layer is formulated using hydroxypropyl methylcellulose K15M, ethyl cellulose, xanthan gum and guar gum in various ratios to delay the drug release. FT-IR studies for excipients are tested for compatibility with the drug. Eva.. Read More»

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Google Scholar citation report
Citations: 533

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