Journal of Dermatology and Dermatologic Diseases

Sherif S Awad

Publications

• Review Article
  Behavior of Hair Follicles in Vitiligo: Clinical Presentation and Discussion
  Author(s): Sherif S AwadSherif S Awad
  
  The color of the hair is dependent on the existence and function of the melanin producing cells, the melanocytes, in the hair matrix of the bulb. In vitiligo, the loss of color of the affected skin is due to loss of epidermal melanocytes, which may also be accompanied by loss of the bulbar melanocytes with subsequent loss of the hair color. Lymphocytic immune-cytotoxic process maybe involved in the destruction of epidermal or bulbar melanocytes. Hair depigmentation is said to follow surface depigmentation in long standing disease. This delay in development of leukotrichia in vitiligo could be claimed to the difference in melanization nature of hair follicle in comparison to epidermal melanization process. In rare cases, follicular melanocytes can be primarily destroyed in vitiligo without destruction of epidermal melanocytes. Apart from mature melanocytes, the hair follicles possess a.. Read More»
  DOI: 10.4172/2376-0427.1000120

  Abstract PDF