Egypt
Research Article
Morphometrical, Histopathological, and Cytogenetical Ameliorating Effects of Green Tea Extract on Nicotine Toxicity of the Testis of Rats
Author(s): Azza M Gawish, Sherin Ramadan, Aziza M Hassan and Aliaa M IssaAzza M Gawish, Sherin Ramadan, Aziza M Hassan and Aliaa M Issa
This current study aimed at evaluating the toxic effect of nicotine and the possible protective role of green tea extract on some organs of Swiss albino mice by using histological, histomorphometerical a nd cytogenetical studies. Male Swiss albino mice were divided into four groups. The first group served as control and was injected intrapertoneally (i.p.) with distilled water (1ml DW/daily). The second group was injected with green tea extract (40 mg/ kg.b.w./i.p./ daily), animals of the third group were injected with nicotine (2.5 mg/kg.b.w./i.p. daily) and those of the fourth group were injected with nicotine (2.5 mg/kg.b.w./i.p/daily) and green tea extract (40 mg/ kg.b.w./i.p./daily). The experimental period was four successive weeks. Nicotine treatment induced histological changes in both the lung and testicular tissue as revealed by light microscope. It also induced histomorphol.. Read More»
DOI:
10.4172/2157-7099.1000105
Journal of Cytology & Histology received 2476 citations as per Google Scholar report