Medicinal Chemistry

Shettima YA

Publications

• Research Article
  Isolation and Structural Elucidation of 20 Hydroxyecdystone from Vitex doniana Sweet Stem bark (Black plum) Mustapha
  Author(s): Tijjani A, Shettima YA, Abdulrahman FI, Khan IZ, Tom GM and Cong LITijjani A, Shettima YA, Abdulrahman FI, Khan IZ, Tom GM and Cong LI
  
  Vitex doniana Sweet, a plant commonly known black plum, in English, Prunier noir in French, dinya in Hausa, ucha koro in Igbo, oori-nla in yoruba and ngarmi in Kanuri is a medium-sized deciduous tree, 8-18 m high, with a heavy rounded crown and a clear bole up to 5 m. V. doniana is from Verbenaceae family and abundantly occurring in savannah regions. It can be found throughout tropical Africa. The ethanolic extract of Vitex doniana stem bark (11.9 g) was subjected to a silica gel accelerated column chromatography and eluents fractions (150 ml aliquots) obtained were collected and monitored with thin layer chromatography (TLC). Fractions with similar Rf values from same solvents system were poled together. Phytochemical test of all the fractions were perform. Complete elution yielded 48 fractions (150 ml/fraction) which were pooled to 24 fractions an.. Read More»
  DOI: 10.4172/2161-0444.1000436

  Abstract PDF